If you love hearty comfort food with bold flavors, this Pepperoni Beef Enchiladas Bake is going to be a hit in your kitchen. It combines tender tortillas filled with seasoned ground beef, melted cheese, rich enchilada sauce, and a surprising but delicious topping of pepperoni slices. The result is a fusion of Mexican-inspired enchiladas with a touch of pizza-style flavor—cheesy, saucy, and incredibly satisfying.
This dish is perfect for family dinners, potlucks, or a cozy weekend meal when you want something easy yet irresistibly delicious.
A Cozy, Flavor-Packed Dinner
These enchiladas are loaded with savory beef, onions, and cheese, then rolled tightly in flour tortillas before being smothered in a bold, flavorful red sauce. After assembling, they’re topped with a generous layer of melted cheese and pepperoni slices, bringing a smoky and slightly spicy kick that makes this dish unforgettable.
Once baked, everything melds together into a gooey, saucy, cheesy masterpiece that fills the whole kitchen with amazing aromas.
Ingredients You’ll Need
- Flour tortillas
- Ground beef
- Shredded cheese (cheddar, Monterey Jack, or a blend)
- Red enchilada sauce
- Pepperoni slices
- Onion, diced
- Garlic, minced
- Olive oil
- Chili powder
- Paprika
- Cumin
- Salt and pepper
- Optional: Beans, diced bell peppers, jalapeños, fresh cilantro
How to Make Pepperoni Beef Enchiladas Bake
1. Prepare the Beef Filling
Heat a bit of olive oil in a skillet. Add diced onions and sauté until softened. Add ground beef and cook until browned. Stir in garlic, chili powder, paprika, cumin, salt, and pepper. Mix well, then simmer until the flavors blend beautifully.
If you prefer, you can also add beans or diced peppers for extra texture.
2. Assemble the Enchiladas
Lay flour tortillas flat and fill each with a spoonful of the beef mixture and shredded cheese. Roll each tortilla tightly and place them seam-side down in a greased baking dish.
3. Add Sauce and Cheese
Pour enchilada sauce generously over the rolled tortillas, making sure every part gets coated. Sprinkle more cheese on top, covering the entire dish.
Finally, add a layer of pepperoni slices evenly across the top—this step gives the dish its delicious fusion twist.
4. Bake to Perfection
Preheat your oven to 375°F (190°C). Bake the enchiladas for about 20–25 minutes or until the cheese is melted, bubbly, and lightly golden around the edges.
5. Garnish and Serve
Once out of the oven, let the dish rest for a few minutes so everything sets nicely. Garnish with chopped cilantro or parsley if desired.
Serve hot with sour cream, guacamole, or a fresh green salad.
Why You’ll Love This Dish
- Easy to assemble with simple ingredients
- Perfect comfort food—warm, filling, and deeply flavorful
- Customizable to suit your taste (spicy, mild, loaded with veggies, etc.)
- The pepperoni twist adds a fun and tasty layer of flavor
- Feeds the whole family with ease
Whether you’re craving something cheesy, meaty, or saucy, this Pepperoni Beef Enchiladas Bake checks every box. It’s a guaranteed crowd-pleaser and an excellent dish for adding creativity to your dinner routine. Enjoy every bite!